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1.
J Health Popul Nutr ; 42(1): 23, 2023 03 24.
Artículo en Inglés | MEDLINE | ID: mdl-36964631

RESUMEN

BACKGROUND: Many studies show that people who eat a balanced diet have stronger immunity. The present work aimed to identify the effects of the diet history of COVID-19 patients having recovered from the disease on the occurrence and severity of symptoms. METHODS: The study sample consisted of 346 individuals aged 20-65 years. The participants' data and answers to an electronic questionnaire regarding their diet history and symptoms were collected. The study focused on four hard symptoms (fever, body pain, cough, and dyspnoea) to investigate the relationship between these symptoms and the consumption of specific immunity foods. RESULTS: Symptoms were reported by 88.1% of the participants eating none of the foods investigated, whereas 85.54% and 85.55% of the individuals with little or intensive food intake, respectively, experienced symptoms. CONCLUSIONS: Intake of specific functional foods might slightly reduce the occurrence of some symptoms.


Asunto(s)
COVID-19 , Humanos , Alimentos , Encuestas y Cuestionarios , Dieta
2.
J Cancer Res Clin Oncol ; 149(9): 6239-6246, 2023 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-36702973

RESUMEN

PURPOSE: The study aimed to compare the dosimetric results and treatment delivery efficiency among four techniques to explore the preferred technique in prostate treatment. MATERIALS AND METHODS: 7 IMRT, 9 IMRT, 1 ARC, and 2 ARC plans were created for 30 prostate cancer patients using the Eclipse™ treatment planning system (Varian Medical Systems). All the plans were designed to deliver 80.0 Gy in 40 fractions to the prostate planning target volume (PTV). Target coverage, organs at risk (OARs), number of monitor units, homogeneity, and conformity were compared across the four techniques to assess the quality of the plans. RESULTS: The study revealed better Planning Target Volume (PTV) dose coverage in the VMAT-2A than in the other plans. At the same time, VMAT-2A plans were found to be significantly lower in terms of Bladder and rectum doses than other techniques. In addition, VMAT has the advantage of considerably reducing the number of monitor units and treatment time. CONCLUSION: For prostate cancer, VMAT may offer a favorable dose gradient profile, conformity, and MU and treatment time compared to IMRT.


Asunto(s)
Neoplasias de la Próstata , Radioterapia de Intensidad Modulada , Masculino , Humanos , Radioterapia de Intensidad Modulada/métodos , Dosificación Radioterapéutica , Radiometría , Neoplasias de la Próstata/radioterapia , Planificación de la Radioterapia Asistida por Computador/métodos
3.
Luminescence ; 37(8): 1376-1386, 2022 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-35708545

RESUMEN

Linen fibres were coated with a glow-in-the-dark photoluminescence, flame-retarding, and hydrophobic smart nanocomposite using the pad-dry-curing process. Ecologically friendly ammonium polyphosphate and lanthanide-activated strontium aluminium oxide (LSAO) nanoparticles were immobilized into linen fabric using eco-friendly room-temperature-vulcanizing silicone rubber. Different analytical techniques were used to examine the morphological characteristics and elemental compositions of LSAO nanoparticles and treated linen textiles. The self-extinguishing properties of the treated linen textiles were tested for their fire resistance. After 24 washing cycles, the coated linen samples retained their flame-retarding properties. The treated linen's superhydrophobicity rose in direct proportion to the LSAO concentration. After being excited at 365 nm, the colourless luminescent film that was coated on linen surface gave out an emission wavelength of 519 nm. The photoluminescent linen was monitored to create a range of different colours, including off-white in daytime light and green under ultraviolet (UV) light radiation, according to the Commission Internationale de l'éclairage laboratory colorimetric coordinates and photoluminescence spectra. Emission, excitation, and lifetime spectral analysis of the treated linen revealed persistent phosphorescence. For mechanical and comfort evaluation, the coated linen textiles' bending length and air permeability were assessed. Good UV light shielding and enhanced antibacterial activity were detected in the treated linens.


Asunto(s)
Nanopartículas , Textiles , Óxido de Aluminio , Antibacterianos/química , Ropa de Cama y Ropa Blanca , Luminiscencia , Nanopartículas/química , Estroncio
4.
Radiat Prot Dosimetry ; 198(7): 423-433, 2022 Jun 09.
Artículo en Inglés | MEDLINE | ID: mdl-35639601

RESUMEN

OBJECTIVE: To establish national diagnostic reference levels (NDRLs) for most common paediatric computed tomography (CT) examinations in Egypt. METHODS: This was a prospective study that included all dedicated paediatric imaging centers in Egypt. Data from 1680 individual paediatric patients undergoing CT scanning of the head, chest and abdomen-pelvis were collected. Computed tomography dose indices were recorded, data were analysed and compared with the internationally published paediatric DRLs in14 countries. RESULTS: The Egyptian NDRLs of the CTDIvol (mGy) for head, chest and abdomen-pelvis scans among four paediatric age groups were found to be (23, 27, 28, 32, 4, 5, 6, 8, 5, 6, 7, 9) mGy, respectively; and the corresponding NDRLs of the DLP (mGycm) for head, chest and abdomen-pelvis scans were found to be (345, 428, 499, 637, 67, 85, 145, 215, 97, 135, 240, 320) mGycm, respectively. There were variations in the radiation doses between CT centers and identical scanners indicating the need for dose optimization. The NDRLs of the CTDIvol (mGy) and the DLP (mGycm) values were similar to or lower than international DRLs. CONCLUSION: This study summarizes the results of the first Egyptian Computed Tomography survey that provides national diagnostic reference levels for paediatric patients in Egypt. Despite the reasonable NDRLs values, the study depicted certain pros and cons concerning CT practice, and identified some problems that hinder the process of optimization as well as justification in children.


Asunto(s)
Niveles de Referencia para Diagnóstico , Tomografía Computarizada por Rayos X , Niño , Egipto , Humanos , Estudios Prospectivos , Dosis de Radiación , Valores de Referencia , Tomografía Computarizada por Rayos X/métodos
5.
Nanomaterials (Basel) ; 12(6)2022 Mar 11.
Artículo en Inglés | MEDLINE | ID: mdl-35335743

RESUMEN

As a contribution to the graphene-based nanoferrite composites, this article is intended to present Mn, Co, and Co-Mn nanoferrites for the preparation and investigation of such samples. Nanoparticles of Co ferrite, Mn ferrite, and Co-Mn ferrite were chemically synthesized by the coprecipitation method. The composites of ferrite/graphene were made by incorporating weight ratios of 25% graphene to 75% ferrite. Various structural and characterizing investigations of ferrite samples and ferrite/graphene composites were performed, including XRD, EDX, SEM, VSM hysteresis loops, AC conductivity, and dielectric behavior. The investigations ensured the formation of the intended nanoferrite powders, each having a single-phase crystal structure with no undesired phases or elements. All samples exhibit a soft magnetic behavior. They show a semiconducting behavior of AC electrical conductivity as well. This was proved by the temperature dependence of the AC's electrical conductivity. Whereas the dielectric function and loss tangent show an expected, well-explained behavior, the ferrite/graphene composite samples have lower saturation magnetization values, lower AC conductivity, and dielectric constant values than the pure ferrites but still have the same behavior trends as those of the pure ferrites. The values obtained may represent steps on developing new materials for expected applications, such as manufacturing supercapacitors and/or improved battery electrodes.

6.
Water Sci Technol ; 82(12): 3047-3061, 2020 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-33341792

RESUMEN

Understanding the microbial ecology of a system allows linking members of the community and their metabolic functions to the performance of the wastewater bioreactor. This study provided a comprehensive conceptual framework for microbial communities in wastewater treatment electro-bioreactors (EBRs). The model was based on data acquired from monitoring the effect of altering different bioreactor operational parameters, such as current density and hydraulic retention time, on the microbial communities of an EBR and its nutrient removal efficiency. The model was also based on the 16S rRNA gene high-throughput sequencing data analysis and bioreactor efficiency data. The collective data clearly demonstrated that applying various electric currents affected the microbial community composition and stability and the reactor efficiency in terms of chemical oxygen demand, N and P removals. Moreover, a schematic that recommends operating conditions that are tailored to the type of wastewater that needs to be treated based on the functional microbial communities enriched at specific operating conditions was suggested. In this study, a conceptual model as a simplified representation of the behavior of microbial communities in EBRs was developed. The proposed conceptual model can be used to predict how biological treatment of wastewater in EBRs can be improved by varying several operating conditions.


Asunto(s)
Microbiota , Purificación del Agua , Reactores Biológicos , ARN Ribosómico 16S/genética , Eliminación de Residuos Líquidos , Aguas Residuales
7.
Mater Sci Eng C Mater Biol Appl ; 96: 708-715, 2019 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-30606584

RESUMEN

Novel coating for stainless steel stent was developed. Graphene sheets were exfoliated directly in chitosan solution as biopolymer and then decorated with TiO2 nanoparticles of an average size of 21 nm. Coating solutions of chitosan, graphene sheets and graphene sheets decorated TiO2NPs were coated on stainless steel stent in uniform form. The average thickness of the coated layer was found to be 6 and 10.6 µm for graphene and TiO2NPs decorated graphene coatings, respectively. The mechanical properties and hematological properties of the developed coated and uncoated stents were studied. The graphene sheets based coated stent showed good mechanical properties compared to chitosan and decorated coated stents. Furthermore, the mechanical properties of the coating layer based graphene on stent surface were investigated reflecting very good mechanical properties compared to graphene nanoparticles decorated coating layer. Also, the coated stent based on graphene sheets reflects very good behaviour regarding no platelets adhesion in healthy and diabetic human blood compared to uncoated, chitosan and TiO2NPs decorated graphene coated stents. The graphene sheets and their decorated composites with TiO2NPs were characterized using transmission electron microscopy. Also, the uncoated and coated stents morphologies were evaluated using scanning electron microscopy. This study presents new approach for developing and engineering medical stent using green and cost-effective graphene sheets for enhancing its performance.


Asunto(s)
Plaquetas/metabolismo , Materiales Biocompatibles Revestidos/química , Grafito/química , Ensayo de Materiales , Nanopartículas/química , Adhesividad Plaquetaria , Stents , Humanos , Acero Inoxidable/química
9.
Artículo en Inglés | MEDLINE | ID: mdl-27267278

RESUMEN

The photo-induced interaction of three different sizes of thioglycolic acid (TGA)-capped CdTe quantum dots (CdTe QDs) with two monomethine cyanine dyes belonging to the thiazole orange (TO) family has been studied. Positively charged cyanines interact with QDs surface which is negatively charged due to capping agent carboxylate ions. The energy transfer parameters including Stern-Volmer constant, Ksv, number of binding sites, n, quenching sphere radius, r, the critical energy transfer distance, R0, and energy transfer efficiencies, E have been calculated. The effect of structure and the number of aggregating molecules have been studied as a function of CdTe QDs particle size. Combining organic and inorganic semiconductors leads to increase of the effective absorption cross section of the QDs which can be utilized in novel nanoscale designs for light-emitting, photovoltaic and sensor applications. A synthesized triplet emission of the studied dyes was observed using CdTe QDs as donors and this is expected to play a potential role in molecular oxygen sensitization and in photodynamic therapy (PDT) applications.


Asunto(s)
Compuestos de Cadmio/química , Carbocianinas/química , Colorantes/química , Puntos Cuánticos/química , Telurio/química , Tioglicolatos/química , Transferencia de Energía , Tamaño de la Partícula , Puntos Cuánticos/ultraestructura , Espectrometría de Fluorescencia , Termodinámica
10.
J Nanosci Nanotechnol ; 15(5): 3809-15, 2015 May.
Artículo en Inglés | MEDLINE | ID: mdl-26505009

RESUMEN

Zinc oxide nanomaterials were synthesized with small amounts of magnetic ions to create dilute magnetic semiconductors (DMS), by using a low temperature sol-gel method. Conditions were controlled such that a range of amounts of Co, Ni and Mn were incorporated. The incorporation could be tracked by color changes in the powders to blue for Co, green for Ni and yellow for Mn. XRD measurements showed the ZnO has the wurtzite structure with crystallites 8-12 nm in diameter. Nanoparticles were observed by SEM and TEM and TEM showed that the lattice fringes of different nanoparticles align. Nanoparticle alignment was disrupted when high concentrations of metal dopants were incorporated. Magnetic measurements showed a change in behavior from diamagnetic to paramagnetic with increasing concentration of metal dopants.

11.
East Mediterr Health J ; 21(9): 665-70, 2015 Oct 02.
Artículo en Inglés | MEDLINE | ID: mdl-26450863

RESUMEN

Hand hygiene of health-care staff is one of the most important interventions in reducing transmission of nosocomial infections. This qualitative study aimed to understand the behavioural determinants of hand hygiene in order to develop sustainable interventions to promote hand hygiene in hospitals. Fourteen focus group discussions were conducted with nurses in 2 university hospitals in Egypt. The interviews were tape recorded and transcribed. Thematic analysis was conducted by 2 independent investigators. The findings highlighted that nurses did not perceive the benefits of hand hygiene, and that they linked the need to wash hands to a sense of dirtiness. Knowledge of hand hygiene and related products was limited and preference for water and soap was obvious. Environmental constraints, lack of role models and social control were identified as barriers for compliance with hand hygiene. A multi-faceted hand hygiene strategy was developed based on existing cultural concepts valued by the hospital staff.


Asunto(s)
Comunicación , Infección Hospitalaria/prevención & control , Higiene de las Manos , Control de Infecciones/normas , Personal de Hospital , Características Culturales , Egipto , Femenino , Grupos Focales , Humanos , Masculino
12.
East. Mediterr. health j ; 21(9): 665-670, 2015.
Artículo en Inglés | WHO IRIS | ID: who-255314

RESUMEN

Hand hygiene of health-care staff is one of the most important interventions in reducing transmission of nosocomial infections. This qualitative study aimed to understand the behavioural determinants of hand hygiene in order to develop sustainable interventions to promote hand hygiene in hospitals. Fourteen focus group discussions were conducted with nurses in 2 university hospitals in Egypt. The interviews were tape recorded and transcribed. Thematic analysis was conducted by 2 independent investigators. The findings highlighted that nurses did not perceive the benefits of hand hygiene, and that they linked the need to wash hands to a sense of dirtiness. Knowledge of hand hygiene and related products was limited and preference for water and soap was obvious. Environmental constraints, lack of role models and social control were identified as barriers for compliance with hand hygiene. A multi-faceted hand hygiene strategy was developed based on existing cultural concepts valued by the hospital staff


L'hygiène des mains du personnel de santé est l'une des interventions les plus importantes pour réduire la transmission des infections nosocomiales. Une étude qualitative visait à comprendre les determinants comportementaux de l'hygiène des mains afin d'établir des interventions durables pour la promotion de ce type d'hygiène dans les hôpitaux.Quatorze discussions thématiques en groupes ont été organisées avec le personnel infirmier dans deux hôpitaux universitaires en Egypte.Les entretiens ont été enregistrés puis retranscrits.Une analyse thématique a été menée par deux chercheurs indépendants. Les résultats ont mis en évidence le fait que le personnel infirmier ne percevait pas les avantages de l'hygiène des mains, et qu'il reliait le besoin de se laver les mains à une sensation de saleté. Les connaissances en matière d'hygiène des mains et des produits à utiliser étaient limitées et la préférence pour l'eau et le savon était marquée. Les contraintes environnementales, l'absence de modèles à suivre et de contrôle social ont été identifiés comme des obstacles au respect de l'hygiène des mains. Une stratégie d'hygiène des mains multidimensionelle a été mise au point à partir des concepts culturels existants qui étaient importants pour le personnel hospitalier


Asunto(s)
Higiene de las Manos , Desinfección de las Manos , Infección Hospitalaria , Enfermeras y Enfermeros , Atención a la Salud
13.
Middle East J Anaesthesiol ; 20(5): 695-702, 2010 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-20803859

RESUMEN

OBJECTIVE: The aim of the present study was to evaluate the ease and reliability of the anterior and lateral approaches to sciatic nerve block compared to the posterior parasacral approach, and their suitability for the specific factors in the patients, positions, and surgeries. Also, the insertion and usefulness of the continuous catheter technique was evaluated. METHODS: The study was carried out on 120 patients, ASA I, II and III, of both genders, age range between 20 and 70 years, scheduled for orthopedic, general and vascular lower limb surgery. Patients were enrolled in a prospective, randomized, double blind study. Patients were divided into three equal groups, 40 patients each. All the patients received femoral nerve block in addition to sciatic nerve block either parasacral (Posterior group), lateral (Lateral group) or anterior approach (Anterior group). This was followed by continuous femoral and sciatic nerve blocks in the postoperative period. Patients were assessed as regards the time, duration and intensity of the sensory and motor blocks and also the postoperative analgesia offered by the continuous block. They were also assessed for the hemodynamic changes accompanied these blocks. Radiological study was made to demonestrate the spread of different volumes of the drugs alongside the course of the sciatic nerve. RESULTS: The posterior parasacral approach is the easiest technique to perform and used successfully even in obese patients, but difficult to be done, if at all, in patients with limited movement such as multi-pelvic fractures. The anterior approach was found to be the best for the patients in the supine position, with best results as regards patients' satisfaction and sensory and motor blocks. Only, it is a technique that needs high experience especially in obese patients. The lateral approach was the least performed technique especially its high approach. However, it is useful in patients in supine position, and gives the best results in thin patients. The technique showed to be extremely difficult in obese patients. CONCLUSION: The insertion of a catheter for continuous nerve block was easy. These blocks provided good or excellent postoperative analgesia for all patients in the different groups and facilitated early mobilization which helped in preventing the lower limb srugery - related morbidity and mortality.


Asunto(s)
Bloqueo Nervioso/métodos , Nervio Ciático , Adulto , Anciano , Método Doble Ciego , Femenino , Humanos , Extremidad Inferior/cirugía , Masculino , Persona de Mediana Edad , Satisfacción del Paciente , Estudios Prospectivos
14.
East Mediterr Health J ; 16(2): 134-40, 2010 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-20799563

RESUMEN

Viral hepatitis is a major problem in Egypt. To define the epidemiology of the disease, sentinel surveillance was established in 5 hospitals in diverse areas of the country in 2001. Data were completed for patients meeting the case definition for viral hepatitis. Of a total of 5909 patients evaluated, 4189 (70.9%) showed positive antibody markers for hepatitis. Out of those, 40.2% had evidence of hepatitis A virus (HAV) infection, 30.0% hepatitis B virus (HBV) and 29.8% hepatitis C virus (HCV) infection. This surveillance system was useful in identifying the variable endemicity of acute HAV infection in different regions and for better understanding the epidemiology of HBV and HCV infection.


Asunto(s)
Hepatitis A/epidemiología , Hepatitis B/epidemiología , Hepatitis C/epidemiología , Vigilancia de Guardia , Enfermedad Aguda , Adolescente , Adulto , Distribución por Edad , Niño , Preescolar , Egipto/epidemiología , Enfermedades Endémicas/estadística & datos numéricos , Femenino , Hepatitis A/diagnóstico , Hepatitis A/transmisión , Hepatitis B/diagnóstico , Hepatitis B/transmisión , Hepatitis C/diagnóstico , Hepatitis C/transmisión , Humanos , Masculino , Persona de Mediana Edad , Características de la Residencia , Factores de Riesgo , Estaciones del Año , Estudios Seroepidemiológicos , Distribución por Sexo
15.
East Mediterr Health J ; 16(1): 4-9, 2010 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-20214150

RESUMEN

Hepatitis B virus (HBV) infection is a significant health problem in Egypt. To better define risk factors associated with HBV transmission, we conducted a case-control study among patients admitted with acute hepatitis to an infectious disease hospital in Cairo. A total of 60 cases and 120 controls were interviewed about various exposures within 6 months prior to admission. Univariate analysis revealed HBV case-patients were more likely to report providing injections to relatives or friends, injecting drug use, exposure to a household contact with hepatitis, exposure to invasive medical procedures and being in the military. Efforts should be made to implement strict infection control standards in Egypt.


Asunto(s)
Hepatitis B/epidemiología , Hepatitis B/transmisión , Enfermedad Aguda , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Análisis de Varianza , Estudios de Casos y Controles , Niño , Preescolar , Egipto/epidemiología , Composición Familiar , Femenino , Hepatitis B/etiología , Humanos , Inyecciones/efectos adversos , Masculino , Persona de Mediana Edad , Personal Militar , Factores de Riesgo , Encuestas y Cuestionarios , Reacción a la Transfusión , Sexo Inseguro , Adulto Joven
16.
(East. Mediterr. health j).
en Inglés | WHO IRIS | ID: who-117830

RESUMEN

Viral hepatitis is a major problem in Egypt. To define the epidemiology of the disease, sentinel surveillance was established in 5 hospitals in diverse areas of the country in 2001. Data were completed for patients meeting the case definition for viral hepatitis. Of a total of 5909 patients evaluated, 4189 [70.9%] showed positive antibody markers for hepatitis. Out of those, 40.2% had evidence of hepatitis A virus [HAV] infection, 30.0% hepatitis B virus [HBV] and 29.8% hepatitis C virus [HCV] infection. This surveillance system was useful in identifying the variable endemicity of acute HAV infection in different regions and for better understanding the epidemiology of HBV and HCV infection


Asunto(s)
Hepatitis Viral Humana , Hepatitis A , Hepatitis B , Hepatitis C , Ensayo de Inmunoadsorción Enzimática
17.
(East. Mediterr. health j).
en Inglés | WHO IRIS | ID: who-117808

RESUMEN

Hepatitis B virus [HBV] infection is a significant health problem in Egypt. To better define risk factors associated with HBV transmission, we conducted a case-control study among patients admitted with acute hepatitis to an infectious disease hospital in Cairo. A total of 60 cases and 120 controls were interviewed about various exposures within 6 months prior to admission. Univariate analysis revealed HBV case-patients were more likely to report providing injections to relatives or friends, injecting drug use, exposure to a household contact with hepatitis, exposure to invasive medical procedures and being in the military. Efforts should be made to implement strict infection control standards in Egypt


Asunto(s)
Factores de Riesgo , Estudios de Casos y Controles , Hepatitis B
18.
East Mediterr Health J ; 15(6): 1440-8, 2009.
Artículo en Inglés | MEDLINE | ID: mdl-20218136

RESUMEN

This study assessed the frequency of and rationale for use of injections at health care facilities in Egypt based on WHO core drug use indicators. We reviewed 1406 prescriptions in 43 randomly selected hospitals and primary health care clinics in 2 governorates in Upper and Lower Egypt in 2001. Patients received an injection at 18.1% of encounters. The most frequently prescribed parenteral drugs were anti-infectives (56.9% of injections) and analgesics (13.7%). Injections were more often prescribed in hospitals than in primary health care clinics and in rural than in urban settings. Most injections (94.7%) could have been replaced by a suitable oral preparation. Further efforts are needed to enforce the essential medicines programme in Egypt to improve rational drug prescribing.


Asunto(s)
Prescripciones de Medicamentos/estadística & datos numéricos , Inyecciones Intramusculares/estadística & datos numéricos , Selección de Paciente , Pautas de la Práctica en Medicina/estadística & datos numéricos , Procedimientos Innecesarios/estadística & datos numéricos , Adolescente , Adulto , Analgésicos/uso terapéutico , Antiinfecciosos/uso terapéutico , Niño , Preescolar , Revisión de la Utilización de Medicamentos , Medicamentos Esenciales/uso terapéutico , Egipto , Femenino , Hospitales Públicos , Humanos , Lactante , Masculino , Persona de Mediana Edad , Atención Primaria de Salud
19.
(East. Mediterr. health j).
en Inglés | WHO IRIS | ID: who-117782

RESUMEN

This study assessed the frequency of and rationale for use of injections at health care facilities in Egypt based on WHO core drug use indicators. We reviewed 1406 prescriptions in 43 randomly selected hospitals and primary health care clinics in 2 governorates in Upper and Lower Egypt in 2001. Patients received an injection at 18.1% of encounters. The most frequently prescribed parenteral drugs were anti-infectives [56.9% of injections] and analgesics [13.7%]. Injections were more often prescribed in hospitals than in primary health care clinics and in rural than in urban settings. Most injections [94.7%] could have been replaced by a suitable oral preparation. Further efforts are needed to enforce the essential medicines programme in Egypt to improve rational drug prescribing


Asunto(s)
Vías de Administración de Medicamentos , Pautas de la Práctica en Medicina , Hepatitis C , Prescripciones de Medicamentos , Inyecciones
20.
J Laryngol Otol ; 121(10): 962-7, 2007 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-17295933

RESUMEN

INTRODUCTION: Chronic, persistent cough is a common clinical problem, the cause of which sometimes remains unidentifiable. AIMS: To study a potential association between Helicobacter pylori infection and chronic, persistent cough. MATERIALS AND METHODS: A clinical observational study with symptom analysis, including 162 patients whose main presenting complaint was chronic, persistent cough of unidentifiable cause (study group) and 42 patients with chronic, non-specific laryngopharyngeal manifestations not including chronic cough (control group). RESULTS: Active H pylori infection was present in 86.4 per cent (140/162) of patients in the chronic cough group, as opposed to 45.2 per cent (19/42) of the control group, as confirmed by detection of H pylori antigen in stool specimens. This difference was statistically significant (p<0.001). There was a significant improvement of the chronic cough of 75.4 per cent (98/130) of patients after successful H pylori eradication using appropriate medical therapy (p<0.001). CONCLUSIONS: Helicobacter pylori infection may lead to laryngopharyngeal irritation, with several clinical manifestations including chronic, persistent cough. However, the exact mechanism of this requires further research.


Asunto(s)
Tos/etiología , Infecciones por Helicobacter/complicaciones , Helicobacter pylori , Adulto , Estudios de Casos y Controles , Tos/microbiología , Femenino , Humanos , Laringoscopía/métodos , Masculino , Persona de Mediana Edad , Encuestas y Cuestionarios , Resultado del Tratamiento
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